Medical History

Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis.

In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. "It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat," Muhammad H. Zaman warns.

The Biography of Resistance is Zaman's riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis--including war, greed, natural disasters, and germophobia--to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe.

Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

Winner, 2018 PEN/E.O. Wilson Prize for Literary Science Writing
Short-listed for the 2018 Wellcome Book Prize
A Top 10 Science Book of Fall 2017, Publishers Weekly
A Best History Book of 2017, The Guardian

Warning: She spares no detail! --Erik Larson, bestselling author of Dead Wake

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of nineteenth-century surgery and shows how it was transformed by advances made in germ theory and antiseptics between 1860 and 1875. She conjures up early operating theaters--no place for the squeamish--and surgeons, who, working before anesthesia, were lauded for their speed and brute strength. These pioneers knew that the aftermath of surgery was often more dangerous than patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the riddle and change the course of history.

Fitzharris dramatically reconstructs Lister's career path to his audacious claim that germs were the source of all infection and could be countered by a sterilizing agent applied to wounds. She introduces us to Lister's contemporaries--some of them brilliant, some outright criminal--and leads us through the grimy schools and squalid hospitals where they learned their art, the dead houses where they studied, and the cemeteries they ransacked for cadavers.

Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

Finalist for the Pulitzer Prize in General Nonfiction
Longlisted for the Andrew Carnegie Medal for Excellence in Nonfiction
Winner of the WSU AOS Bonner Book Award

The New York Times bestseller from physician and award-winning writer Louise Aronson--an essential, empathetic look at a vital but often disparaged stage of life, as revelatory as Atul Gawande's Being Mortal.

For more than 5,000 years, old has been defined as beginning between the ages of 60 and 70. That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we've made old age into a disease, a condition to be dreaded, denigrated, neglected, and denied.

Reminiscent of Oliver Sacks, noted Harvard-trained geriatrician Louise Aronson uses stories from her quarter century of caring for patients, and draws from history, science, literature, popular culture, and her own life to weave a vision of old age that's neither nightmare nor utopian fantasy--a vision full of joy, wonder, frustration, outrage, and hope about aging, medicine, and humanity itself.

Elderhood is for anyone who is, in the author's own words, an aging, i.e., still-breathing human being.

At the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government's notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions.

The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers--and indeed the whole medical establishment--with such deep distrust.

The New York Times bestseller, now in paperback!
From the celebrated author of Nickel and Dimed, Barbara Ehrenreich explores how we are killing ourselves to live longer, not better.

A razor-sharp polemic which offers an entirely new understanding of our bodies, ourselves, and our place in the universe, NATURAL CAUSES describes how we over-prepare and worry way too much about what is inevitable. One by one, Ehrenreich topples the shibboleths that guide our attempts to live a long, healthy life -- from the importance of preventive medical screenings to the concepts of wellness and mindfulness, from dietary fads to fitness culture.
But NATURAL CAUSES goes deeper -- into the fundamental unreliability of our bodies and even our "mind-bodies," to use the fashionable term. Starting with the mysterious and seldom-acknowledged tendency of our own immune cells to promote deadly cancers, Ehrenreich looks into the cellular basis of aging, and shows how little control we actually have over it. We tend to believe we have agency over our bodies, our minds, and even over the manner of our deaths. But the latest science shows that the microscopic subunits of our bodies make their own "decisions," and not always in our favor.

We may buy expensive anti-aging products or cosmetic surgery, get preventive screenings and eat more kale, or throw ourselves into meditation and spirituality. But all these things offer only the illusion of control. How to live well, even joyously, while accepting our mortality -- that is the vitally important philosophical challenge of this book.

Drawing on varied sources, from personal experience and sociological trends to pop culture and current scientific literature, NATURAL CAUSES examines the ways in which we obsess over death, our bodies, and our health. Both funny and caustic, Ehrenreich then tackles the seemingly unsolvable problem of how we might better prepare ourselves for the end -- while still reveling in the lives that remain to us.

On December 29, 2019, historian Timothy Snyder fell gravely ill. Unable to stand, barely able to think, he waited for hours in an emergency room before being correctly diagnosed and rushed into surgery. Over the next few days, as he clung to life and the first light of a new year came through his window, he found himself reflecting on the fragility of health, not recognized in America as a human right but without which all rights and freedoms have no meaning.

And that was before the pandemic. We have since watched American hospitals, long understaffed and undersupplied, buckling under waves of ill patients. The federal government made matters worse through willful ignorance, misinformation, and profiteering. Our system of commercial medicine failed the ultimate test, and thousands of Americans died.

In this eye-opening cri de coeur, Snyder traces the societal forces that led us here and outlines the lessons we must learn to survive. In examining some of the darkest moments of recent history and of his own life, Snyder finds glimmers of hope and principles that could lead us out of our current malaise. Only by enshrining healthcare as a human right, elevating the authority of doctors and medical knowledge, and planning for our children's future can we create an America where everyone is truly free.

Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening. A brilliantly conceptualized and challenging achievement (Kirkus Reviews), it is essential reading, offering a new perspective on human history.

Wondering whether eating powdered mummies might be just the thing to cure your ills? Tempted by those vintage ads suggesting you wear radioactive underpants for virility? Ever considered drilling a hole in your head to deal with those pesky headaches? Probably not. But for thousands of years, people have done things like this--and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.

Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we're looking at you, raw water!) and be better able to figure out if this is a miracle cure (it's not) or a scam.

Table of Contents:

Part 1: The Unnerving
The Resurrection Men
Opium
An Electrifying Experience
Weight Loss
Charcoal
The Black Plague
Pliny the Elder
Erectile Dysfunction
Spontaneous Combustion
The Doctor Is In
Trepanation

Part II: The Gross
Mummy Medicine
Mercury
The Guthole Bromance
A Piece of Your Mind
The Unkillable Phineas Gage
Phrenology
The Man Who Drank Poop
Robert Liston
Urine Luck!
Radium
Humorism
The Doctor Is In
The Straight Poop

Part III: The Weird
The Dancing Plague
Curtis Howe Springer
Smoke 'Em if You Got ëEm
A Titanic Case of Nausea
Arsenic
Paracelsus
Honey
Self-Experimentation
Homeopathy
The Doctor Is In

Part IV: The Awesome
The Poison Squad
Bloodletting
Death by Chocolate
John Harvey Kellogg
Parrot Fever
Detox
Vinegar
Polio Vaccine
The Doctor Is In

Joining the ranks of modern myth busters, Dr. Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.

So why does disease exist? Moalem proposes that most common ailments--diabetes, hemochromatosis, cystic fibrosis, sickle cell anemia--came into existence for very good reasons. At some point they helped our ancestors survive some grand challenge to their existence. Examining the evolution of man, Moalem reveals the role genetic and cultural differences have played in the health and well-being of various races, including their susceptibility to disease.

With mesmerizing insight, Moalem offers groundbreaking insight into:

- How diabetes may be a biproduct of a mechanism that helped humans survive the Ice Age

- Why African Americans living in the north might suffer from vitamin D deficiencies,

- Why Asians can't drink as much alcohol as Europeans

Revelatory, utterly engaging, and timely--Moalem ponders strongN1, the emerging Avian Flu virus--Why Redheads Feel More Pain and Asians Can't Drink will irrevocably change the way we think about our bodies and ourselves.

WINNER OF THE 2020 PULITZER PRIZE IN GENERAL NONFICTION

The Undying is a startling, urgent intervention in our discourses about sickness and health, art and science, language and literature, and mortality and death. In dissecting what she terms 'the ideological regime of cancer, ' Anne Boyer has produced a profound and unforgettable document on the experience of life itself. --Sally Rooney, author of Normal People

Anne Boyer's radically unsentimental account of cancer and the 'carcinogenosphere' obliterates cliche. By demonstrating how her utterly specific experience is also irreducibly social, she opens up new spaces for thinking and feeling together. The Undying is an outraged, beautiful, and brilliant work of embodied critique. --Ben Lerner, author of The Topeka School

A week after her forty-first birthday, the acclaimed poet Anne Boyer was diagnosed with highly aggressive triple-negative breast cancer. For a single mother living paycheck to paycheck who had always been the caregiver rather than the one needing care, the catastrophic illness was both a crisis and an initiation into new ideas about mortality and the gendered politics of illness.

A twenty-first-century Illness as Metaphor, as well as a harrowing memoir of survival, The Undying explores the experience of illness as mediated by digital screens, weaving in ancient Roman dream diarists, cancer hoaxers and fetishists, cancer vloggers, corporate lies, John Donne, pro-pain "dolorists," the ecological costs of chemotherapy, and the many little murders of capitalism. It excoriates the pharmaceutical industry and the bland hypocrisies of "pink ribbon culture" while also diving into the long literary line of women writing about their own illnesses and ongoing deaths: Audre Lorde, Kathy Acker, Susan Sontag, and others.

A genre-bending memoir in the tradition of The Argonauts, The Undying will break your heart, make you angry enough to spit, and show you contemporary America as a thing both desperately ill and occasionally, perversely glorious.

Includes black-and-white illustrations

In Unwell Women, Elinor Cleghorn traces the almost unbelievable history of how medicine has failed women by treating their bodies as alien and other, often to perilous effect. The result is an authoritative and groundbreaking exploration of the relationship between women and medical practice, from the wandering womb of Ancient Greece to the rise of witch trials across Europe, and from the dawn of hysteria as a catchall for difficult-to-diagnose disorders to the first forays into autoimmunity and the shifting understanding of hormones, menstruation, menopause, and conditions like endometriosis.

Packed with character studies and case histories of women who have suffered, challenged, and rewritten medical orthodoxy--and the men who controlled their fate--this is a revolutionary examination of the relationship between women, illness, and medicine. With these case histories, Elinor pays homage to the women who suffered so strides could be made, and shows how being unwell has become normalized in society and culture, where women have long been distrusted as reliable narrators of their own bodies and pain. But the time for real change is long overdue: answers reside in the body, in the testimonies of unwell women--and their lives depend on medicine learning to listen.